In recent local discussions, the validity of evidence fro intralipid rescue has been challenged. Why?
Discussion:- Despite being included in authoritative guidelines currently being used for anaesthetic emergency training purposes, the evidence for intralipid rescue is not as robust as is commonly perceived. Although some are strong advocates, others regard the evidence as weakly positive for bupivicaine toxicity but very questionable for other local anaesthetics (see References).
Rosenberg PH Current evidence is not in support of lipid rescue therapy in local anaesthetic systemic toxicity Acta Anaesthesiologica Scandinavica 2016; 60:1029–1032
Weinberg G Current evidence supports use of lipid rescue therapy in local anaesthetic systemic toxicity Acta Anaesthesiologica Scandinavica 2017;61: 365–368
Perioperative Talk 