Consult for radical cystectomy

79 M with recent TURBT demonstrating invasive bladder cancer.

Background

  • Invasive bladder and prostate cancer (Gleeson 7)
  • CABG – nil ongoing symptoms
  • AF – apixaban
  • Mild COPD and restrictive defect secondary to central obesity – NYHA III
  • Stage 3 CKD 
  • OSA – moderate/obstructive – not treated
  • BMI 34, central 

Issues

  • Perioperative risks
    • Risk assessment: NSQIP – 50% chance of serious complications, 6% risk of death, 60% risk of discharge to ‘other than home’, 12% delirium
    • ? patient’s ability to manage and cutaneous urinary stoma – currently needs assistance with shopping/cleaning
    • Patient values current independence
  • ? Further Ix warranted for SOBOE
    • SOBOE – previously reviewed by Respiratory physician – likely deconditioned rather than a treatable cause 
    • TTE – nil significant findings (recent medical admission for urosepsis, long lie and myocardial injury – trop 200)
  • Other non-surgical options?
    • Patient has yet to meet with surgical team to discuss diagnosis and treatment options

Discussion

  • High risk procedure
  • Surgical pathway seems likely to lead to loss of independence/function sooner than a non-surgical pathway
  • Patient does not seem likely to engage meaningfully with prehab
  • CPET unlikely to present any information not already known (high periop risk ++)

Plan

  • Discussion with surgeons – alternative options (?RTx) due to periop risks
  • No CPET 
  • Refer to GP for assessment of early cognitive impairment