Cranial Nerve Palsies

R ocular surgery – transfer of eye muscles and eye botox for CN palsy 

Background: 

  • Medullary Cavernoma
    • Recurrent Intracranial haemorrhage 
    • Multiple ICU admissions 
  • Lone living – independent ADL’s 
    • Home supports 
  • DASI 5 MET’s 

Issues: 

  • LMN Facial Nerve palsy – forehead involvement
    • PEG in situ – can now tolerate a normal diet with no choking, or aspiration 
  • Hoarse voice with pronounced dysphonia o Aetiology uncertain – trauma from ICU stay/repeated intubation 
    • Manifestation of cranial bleed? 
    • Previous grade 1 intubation – no record of trauma/difficulty 
    • No red flag symptoms – no dyspnoea, can lie flat, 
    • Vocal changes have been consistent since hospital admission. No deterioration 
    • Nasendoscopy – unilateral VC paralysis 
  • Complex central sleep apnoea – uses CPAP 

Discussion: 

  • Airway plan – ETT vs LMA
    • Unlikely to be suitable to for LMA 
    • Often lengthy 
    • May require muscle relaxation to facilitate muscle transfer 
  • Surgical complexity – unknown.
    • Booked as day procedure 
    • Need to liaise with surgical team 

Plan:

  • Discuss with surgeon 
  • Post-op disposition:ICU 

Obesity, deconditioning, nephrectomy

58 yo F with renal mass → renal clear cell carcinoma and increasing in size 

Background 

  1. Goitre → T3/4 normal and TSH suppressed. 
  2. OSA – CPAP
  3. AF o SVT/rAF post induction previously 
  4. HFpEF 

Issues: 

  • Physical deconditioning
    • BMI 46 
    • Mobilises with wheelchair 
  • Current smoker 
  • Complicated perioperative course – Breast WLE 2023. Poor wound healing post excision and infection. Required re-intubation and ICU post-operatively 
  • Multiple visits to perioperative clinic – decision not to proceed to surgery made by 2 senior anaesthetists based on significant co-morbidities.
    • Recent Cystoscopy and RPG/lithotripsy for renal calculus – uneventful surgery
    • Request for surgery re-submitted 

Discussion 

Perioperative Optimisation 

  • Minimal changes so far with lifestyle modification – obesity, smoking 
  • Recommendation not to proceed is not preclusive 
  • Patient has been extensively counselled on perioperative risk and wishes to proceed. 
  • Issue now is optimisation and prevention of post-operative complications – biggest risk PPC 
  • Risk factors should be re-addressed with the new incentive of a surgery date
    • Weight loss – consider addition of GLP-1 analogue 
    • Smoking cessation – coaching previously offered, consider Champix? 
    • Prehabiliation 

Plan: 

  • Metabolic clinic referral 
  • Prehabilitation 
  • Post op disposition: CPAP, HDU – do not start without HDU bed confirmed given previous extubation failure. 

Unexplained weight loss, cervical laminectomy

84yo lady for cervical laminectomy. 

Background 

  • Spinal canal stenosis – severe, numbness and weakness all 4 limbs, gait and balance affected, incontinence issues. 
  • IHD – NSTEMI 2019, medically mx 
  • HOCM – apical hypertrophy, nil LVOT, EF 65% 
  • Dyslipidaemia 
  • 4WW, assistance with ADLs 
  • DASI 3.3 METS 

Issues: 

  • Unexplained weight loss
    • 20% over 8 months 
    • Anorexia, decreased intake 
    • Concerning for occult malignancy 
  • Surgeons + gastro consulted -> recommended CT/PET scan, endoscopies if anaemic 

Discussion: 

Should surgery proceed? 

  • Non-elective procedure given imaging and clinical e/o myelopathy 
  • Surgeon notes specify that improvement unlikely. Goal is to prevent further decline. 
  • Timing of surgery relative to investigations? 
  • Where possible, Ix should all be undertaken prior to surgery, as a palliative diagnosis may be made which would likely negate surgery 
  • BMJ Best Practice guidelines have a summary regarding the patient with unintentional weight loss – See attached article 

Plan: 

  • Add on TSH, HbA1c 
  • Await imaging 
  • Postpone surgical date 
  • Liaise with surgeons regarding the above 
  • Liaise with gastro team if anaemia identified – availability for urgent endoscopies 

TSR and chronic pain

86 yo M for shoulder replacement 

Background: 

  • PPM – Symptomatic bradycardia 
  • CKD stage 3. 
  • Valvular disease, pulmonary hypertension 
  • BMI 30 

Issues: 

  • Chronic pain neck and shoulder pain – managed with pregabalin and oxycodone
    • Unable to tolerate NSAID’s due to renal impairment 
  • Recent hospital admission
    • Deconditioned +++ 
    • Anaemia Hb 106, Ferritin high, Normal B12/folate, CRP pending, FOBT pending 
    • Delirium – attributed to urosepsis 
  • Shoulder and arm pain exacerbation
    • Background of degenerative cervical spine and radiculopathy 
    • Shoulder pain worsening 
    • Steroid injection with little effect 
    • TSR being considered; Surgeons anticipating difficult and long procedure 

Discussion: 

Options for Pain Management 

  • Non-operative treatment: no improvement with intra-articular steroid injections
    • Interventional pain options include repeat steroid injection, targeting suprascapular nerve 
  • Pain may not be relieved by shoulder replacement
    • High-risk of perioperative complications, particularly delirium and cognitive decline 
  • Anaemia investigations – possible slow recovery from recent illness
    • Differentials include Age related BM failure and occult loss 
    • Discuss with haematologist after checking CRP and Fe studies post urosepsis event tp exclude acute phase rise in ferritin 
    • Consider gastroenterologist opinion if no improvement 

Plan: 

  • Delay operation 
  • Consider non-operative treatment eg target suprascapular nerve 

Pleural effusion and renal failure

76 yo lady for VATS pleurodesis – drainage pleural effusion 

Background 

  • IDDM
    • IHD – CABG 2016, stents x2 since, o Angio 2020 all are occluded except 1 
    • PPM – 3rd degree HB o AF underlying rhythm 
    • Moderate MR 
    • Pulmonary hypertension 

Issues 

Large symptomatic pleural effusion – aetiology unknown

  • Large symptomatic pleural effusion
    • Transudate 
    • Malignancy vs cardiac vs renal overload 
    • Recent Weight loss 
    • Failed conservative treatment – had pigtail catheter inserted and fluid drained. Talc down drain before removal. Immediate reaccumulation 
    • pro BNP > 45 000 
  • ESRD – dialysis dependent o Anuric 
    • Fluid removal limited by limited by hypotension 
    • Hyperkalemia 

Discussion 

Proceed to surgery? 

  • High risk patient – NSQUIP mortality 20% 
  • Non-operative management has failed 

Opportunity for optimisation? 

  • Renal team – any options for dialysis. Renal palliative care team involvement 
  • cardiologist review and advice

Treating symptoms v. investigation of underlying cause

  • Should she have malignancy workup?

Plan 

  • Cardiologist referral –discuss with Dr Collins next week 
  • Discuss with surgical team and renal team regarding requirement for further investigations/optimisation 
  • Suggest referral to renal palliative care